A cross-sectional study on brain structure, brain function, number sense, and cognition in patients with chronic pain, initiated by Dr. Carsten Bantel, University of Oldenburg, Germany.
Structural MRI
Are there changes of gray matter in chronic pain? Is chronic pain associated with premature brain aging?
DTI
Are there changes of white matter microstructure in chronic pain? Is there a decrease of e.g. fractional anisotropy?
Resting state FMRI
Are there differences in brain networks between individuals with chronic pain and controls?
ChroPain 1
- 42 patients with chronic noncancer pain
- 43 healthy age- and sex-matched controls
- T1- and T2-weighted MRI
- Diffusion Tensor Imaging
- Resting state FMRI
- number processing
- cognitive tests
ChroPain 2
- 23 patients with chronic rheumatic pain
- 24 healthy age- and sex-matched controls
- T1- and T2-weighted MRI
- Resting state FMRI
- Task-based FMRI
- Heart rate variability
- number processing
- cognitive tests
Team
- Carsten Bantel
- Peter Sörös
- Melanie Spindler
- Dominique Gronemann
- Leona Buschmann
- Katharina Koch
- Christiane Thiel
Publications
- Gronemann DC et al. medRxiv 2020.04.16.20068197 | PDF
- Sörös P & Bantel C. PAIN 2020;161:641-650 | Reprint Request
- Spindler et al. Front Behav Neurosci 2018;12:165 | PDF
Support
- School of Medicine and Health Sciences, University of Oldenburg (Forschungspool 2015-1)
- Association of North German Universities, Starter Grant, 2020
- Neuroimaging Unit, School of Medicine and Health Sciences, University of Oldenburg (DFG: 3T MRI INST 184/152-1 FUGG and MEG INST 184/148-1 FUGG)
